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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-1-24
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pubmed:abstractText |
Oral contraceptives (OC) containing different types of progestogens induce different sensitivities to activated protein C (APC) measured with the thrombin generation-based APC-resistance test. These differences in APC resistance may be the biological explanation for the differences in thrombotic risk of the various pills. The mechanistic basis of APC resistance observed in OC users is unknown. Our objective was to study the effect of OC on the two main determinants of the APC-resistance test, free protein S and free tissue factor pathway inhibitor (TFPI).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Androstenes,
http://linkedlifedata.com/resource/pubmed/chemical/Contraceptives, Oral, Combined,
http://linkedlifedata.com/resource/pubmed/chemical/Contraceptives, Oral, Hormonal,
http://linkedlifedata.com/resource/pubmed/chemical/Contraceptives, Oral, Synthetic,
http://linkedlifedata.com/resource/pubmed/chemical/Cyproterone Acetate,
http://linkedlifedata.com/resource/pubmed/chemical/Desogestrel,
http://linkedlifedata.com/resource/pubmed/chemical/Ethinyl Estradiol-Norgestrel...,
http://linkedlifedata.com/resource/pubmed/chemical/Levonorgestrel,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Protein S,
http://linkedlifedata.com/resource/pubmed/chemical/drospirenone,
http://linkedlifedata.com/resource/pubmed/chemical/lipoprotein-associated coagulation...
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1538-7836
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
346-51
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pubmed:meshHeading |
pubmed-meshheading:18067603-Activated Protein C Resistance,
pubmed-meshheading:18067603-Adolescent,
pubmed-meshheading:18067603-Adult,
pubmed-meshheading:18067603-Androstenes,
pubmed-meshheading:18067603-Contraceptives, Oral, Combined,
pubmed-meshheading:18067603-Contraceptives, Oral, Hormonal,
pubmed-meshheading:18067603-Contraceptives, Oral, Synthetic,
pubmed-meshheading:18067603-Cyproterone Acetate,
pubmed-meshheading:18067603-Desogestrel,
pubmed-meshheading:18067603-Ethinyl Estradiol-Norgestrel Combination,
pubmed-meshheading:18067603-Female,
pubmed-meshheading:18067603-Humans,
pubmed-meshheading:18067603-Levonorgestrel,
pubmed-meshheading:18067603-Lipoproteins,
pubmed-meshheading:18067603-Middle Aged,
pubmed-meshheading:18067603-Protein S,
pubmed-meshheading:18067603-Thrombophilia
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pubmed:year |
2008
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pubmed:articleTitle |
Different effects of oral contraceptives containing different progestogens on protein S and tissue factor pathway inhibitor.
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pubmed:affiliation |
Department of Gynaecology and Reproductive Medicine, Leiden University Medical Center, Leiden, The Netherlands. haam.vliet@worldonline.nl
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pubmed:publicationType |
Journal Article,
Comparative Study
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