Linked Life Data

18061946

Source:http://linkedlifedata.com/resource/pubmed/id/18061946

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-12-24
pubmed:abstractText
Several studies showed the benefit of purging of acute myeloid leukemia (AML) stem cell transplants. We reported previously that purging by positive selection of CD34+ and CD133+ cells resulted in a 3-4 log tumor cell reduction (TCR) in CD34- and/or CD133- AML, but has been shown to be potentially applicable in only about 50% of cases. Similar to CD34 and CD133, CD90 marks the hematopoietic CD34 positive stem cells capable of full hematopoietic recovery after myeloablative chemotherapy, and therefore, in the present study, we explored whether a similar purging approach is possible using CD90.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1552-4957
pubmed:author
pubmed:copyrightInfo
(c) 2007 Clinical Cytometry Society
pubmed:issnType
Electronic
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
9-16
pubmed:dateRevised
2009-12-11
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Positive selection for CD90 as a purging option in acute myeloid leukemia stem cell transplants.
pubmed:affiliation
Department of Hematology, VU University Medical Center, Amsterdam, The Netherlands.
pubmed:publicationType
Journal Article