Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-1-21
pubmed:abstractText
Isobaric oligosaccharides enzymatically prepared from hyaluronic acid (HA) and N-acetylheparosan (NAH), were distinguished using tandem mass spectrometry. The only difference between the two series of oligosaccharides was the linkage pattern (in HA 1-->3 and in NAH 1-->4) between glucuronic acid and N-acetylglucosamine residues. Tandem mass spectrometry afforded spectra in which glycosidic cleavage fragment ions were observed for both HA and NAH oligosaccharides. Cross-ring cleavage ions 0,2An and 0,2An-h (n is even number) were observed only in GlcNAc residues of NAH oligosaccharides. One exception was an 0,2A2 ion fragment observed for the disaccharide from HA. These cross-ring cleavage fragment ions are useful to definitively distinguish HA and NAH oligosaccharides.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-10492002, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-10497938, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-10872465, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-11217777, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-11473122, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-11919156, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-12056567, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-12121115, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-12443024, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-12443025, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-12467925, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-12491369, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-12621620, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-12972412, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-14531682, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-14966796, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-15047699, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-15426109, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-15590670, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-15658847, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-15679360, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-15862765, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-15862766, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-16000785, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-16081034, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-16330006, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-16394262, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-16465690, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-16503152, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-16834555, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-17056022, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-17293874, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-17383193, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-2054395, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-7018909, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-7626010, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-8366070, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-8798457, http://linkedlifedata.com/resource/pubmed/commentcorrection/18061476-9737951
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1044-0305
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
82-90
pubmed:dateRevised
2011-8-1
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Tandem MS can distinguish hyaluronic acid from N-acetylheparosan.
pubmed:affiliation
Department of Chemistry, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, USA.
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural