|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001175,
umls-concept:C0019682,
umls-concept:C0019699,
umls-concept:C0029921,
umls-concept:C0031327,
umls-concept:C0032659,
umls-concept:C0043476,
umls-concept:C0205419,
umls-concept:C0449435,
umls-concept:C0674428,
umls-concept:C1280500,
umls-concept:C1382176,
umls-concept:C1512456
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|
pubmed:issue |
4
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pubmed:dateCreated |
2008-2-26
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pubmed:abstractText |
The study sought to investigate the relationship between efavirenz exposure and the CYP2B6 516G-->T(*6) genotype in HIV/AIDS outpatients, using pharmacokinetic modelling and simulation.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0031-6970
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
357-65
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18057928-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:18057928-Adult,
pubmed-meshheading:18057928-Algorithms,
pubmed-meshheading:18057928-Aryl Hydrocarbon Hydroxylases,
pubmed-meshheading:18057928-Benzoxazines,
pubmed-meshheading:18057928-Female,
pubmed-meshheading:18057928-Gene Frequency,
pubmed-meshheading:18057928-Genetic Variation,
pubmed-meshheading:18057928-Genotype,
pubmed-meshheading:18057928-HIV Infections,
pubmed-meshheading:18057928-Humans,
pubmed-meshheading:18057928-Male,
pubmed-meshheading:18057928-Models, Statistical,
pubmed-meshheading:18057928-Oxidoreductases, N-Demethylating,
pubmed-meshheading:18057928-Population,
pubmed-meshheading:18057928-Reverse Transcriptase Inhibitors,
pubmed-meshheading:18057928-Sex Factors,
pubmed-meshheading:18057928-Zimbabwe
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pubmed:year |
2008
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pubmed:articleTitle |
High prevalence of the CYP2B6 516G-->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe.
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pubmed:affiliation |
Department of DMPK & BAC, African Institute of Biomedical Science and Technology (AiBST), P.O.Box 2294, Harare, Zimbabwe.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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