rdf:type |
|
lifeskim:mentions |
umls-concept:C0011209,
umls-concept:C0085590,
umls-concept:C0086418,
umls-concept:C0181314,
umls-concept:C0205042,
umls-concept:C0205210,
umls-concept:C0205276,
umls-concept:C0205314,
umls-concept:C0302891,
umls-concept:C0596545,
umls-concept:C0679622,
umls-concept:C1450425,
umls-concept:C1515568,
umls-concept:C1522577,
umls-concept:C2603343
|
pubmed:issue |
4
|
pubmed:dateCreated |
2007-12-6
|
pubmed:abstractText |
A novel antisense phosphorodiamidate morpholino oligomer, AVI-4126, was shown to be effective in reducing neointimal formation in different animal models following delivery by pluronic gels, porous balloon catheters, and coated stents. The purpose of the AVAIL study was to investigate both the safety and the efficacy of AVI-4126 delivered locally via Infiltrator catheter after percutaneous coronary intervention in humans.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1553-8389
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
230-5
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:18053943-Aged,
pubmed-meshheading:18053943-Angioplasty, Balloon, Coronary,
pubmed-meshheading:18053943-Coronary Angiography,
pubmed-meshheading:18053943-Coronary Restenosis,
pubmed-meshheading:18053943-Coronary Stenosis,
pubmed-meshheading:18053943-Drug-Eluting Stents,
pubmed-meshheading:18053943-Female,
pubmed-meshheading:18053943-Follow-Up Studies,
pubmed-meshheading:18053943-Humans,
pubmed-meshheading:18053943-Male,
pubmed-meshheading:18053943-Middle Aged,
pubmed-meshheading:18053943-Morpholines,
pubmed-meshheading:18053943-Morpholinos,
pubmed-meshheading:18053943-Prospective Studies,
pubmed-meshheading:18053943-Treatment Outcome,
pubmed-meshheading:18053943-Ultrasonography, Interventional
|
pubmed:articleTitle |
First human experience with local delivery of novel antisense AVI-4126 with Infiltrator catheter in de novo native and restenotic coronary arteries: 6-month clinical and angiographic follow-up from AVAIL study.
|
pubmed:affiliation |
Lenox Hill Heart and Vascular Institute, New York, NY 10021, USA. nkipshidze@lenoxhill.net
|
pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Multicenter Study,
Clinical Trial, Phase II
|