Source:http://linkedlifedata.com/resource/pubmed/id/18049729
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
47
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pubmed:dateCreated |
2007-11-30
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pubmed:abstractText |
Neutron capture therapy (NCT) is a binary radio-chemotherapeutic modality for the treatment of cancer. A major focus of NCT-related research is the development of novel tumor-selective agents that serve as the chemical component in NCT. Thymidine analogues substituted with a boron-containing carborane cluster at the N3 position, designated 3CTAs (3-carboranyl thymidine analogues), constitute one class of these new improved NCT agents. Their chemical, structural and biological properties are discussed in this Feature Article.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1359-7345
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4978-91
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pubmed:meshHeading |
pubmed-meshheading:18049729-Animals,
pubmed-meshheading:18049729-Boron,
pubmed-meshheading:18049729-Boron Compounds,
pubmed-meshheading:18049729-Disease,
pubmed-meshheading:18049729-Humans,
pubmed-meshheading:18049729-Neutron Capture Therapy,
pubmed-meshheading:18049729-Phosphotransferases,
pubmed-meshheading:18049729-Thymidine
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pubmed:year |
2007
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pubmed:articleTitle |
Carboranyl thymidine analogues for neutron capture therapy.
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pubmed:affiliation |
College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA. tjarks.1@osu.edu
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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