Linked Life Data

18045218

Source:http://linkedlifedata.com/resource/pubmed/id/18045218

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2007-11-29
pubmed:abstractText
Histidine kinases are ubiquitous molecular sensors that are used by bacteria to detect and respond to a myriad of environmental signals. They are attractive antimicrobial targets because of their roles in mediating the virulence of pathogenic organisms, as well as the ability of bacteria to resist host defenses and develop resistance to antibiotics. In this review, we discuss the challenges involved in developing specific inhibitors of this highly diverse group of kinases.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1389-5575
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1144-54
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Histidine kinases as antimicrobial targets: prospects and pitfalls.
pubmed:affiliation
Division of Chemical and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, 306 Carmody Road, St. Lucia QLD 4072, Australia. s.rowland1@uq.edu.au
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't