Linked Life Data

18041997

Source:http://linkedlifedata.com/resource/pubmed/id/18041997

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2007-11-28
pubmed:abstractText
Of the drugs dropped from development in 2006, 11 were being developed for infectious diseases. Of these, nine were for viral diseases, including four against HIV, two against hepatitis C virus and one each against respiratory syncytial virus, severe acute respiratory syndrome (coronavirus) and a variety of viruses. The nine antiviral agents comprised six synthetic small-molecule compounds, one peptide, one monoclonal antibody and a vaccine. The remaining two agents were a vaccine for Pseudomonas aeruginosa infection, and lipid-based agent for septic shock. Each of these drugs is briefly reviewed and reasons for failure are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1744-7658
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1867-78
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Discontinued drugs in 2006: anti-infectives.
pubmed:affiliation
Infectious Diseases, Novartis Institutes for BioMedical Research, Inc., 500 Technology Square, Cambridge, MA 02139, USA. neil.ryder@novartis.com
pubmed:publicationType
Journal Article, Review