Linked Life Data

18041108

Source:http://linkedlifedata.com/resource/pubmed/id/18041108

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-3-17
pubmed:abstractText
The preparation and characterization of surface-PEGylated polymeric nanoparticles are described. These systems were obtained by UV irradiation of PHM and PHM-PEG(2000) as an inverse microemulsion, using an aqueous solution of the PHM/PHM-PEG(2000) copolymer mixture as the internal phase and triacetin saturated with water as the external phase, and characterized by dimensional analysis, zeta-potential measurements and XPS. in vitro biological tests demonstrated their cell compatibility and their ability to escape from phagocytosis. Rivastigmine was encapsulated into the nanoparticle structure and drug-release profiles from loaded samples were investigated in PBS at pH = 7.4 and human plasma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1616-5195
pubmed:author
pubmed:issnType
Electronic
pubmed:day
10
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
247-59
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
A nanoparticulate drug-delivery system for rivastigmine: physico-chemical and in vitro biological characterization.
pubmed:affiliation
Dipartimento di Chimica e Tecnologie Farmaceutiche, Università degli Studi di Palermo, via Archirafi, 32-90123 Palermo, Italy. ema.craparo@unipa.it
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't