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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1992-4-28
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pubmed:abstractText |
We studied the localization of dystrophin in normal human fetal muscle by immunohistochemistry. Our results show the appearance of dystrophin at week 11 and a progressive organization of the protein along membrane in the following weeks of gestation. At week 22 almost all fibers show a clear membrane immunostaining. Concomitant analysis of muscle fiber-type composition reveals no correlation between progressive appearance of dystrophin and muscle fiber-type differentiation. Our findings suggest that synthesis and localization of dystrophin in developing human skeletal muscle is time-related and probably independent of neuronal influences.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0736-5748
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
607-12
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:1803857-Dystrophin,
pubmed-meshheading:1803857-Female,
pubmed-meshheading:1803857-Fetus,
pubmed-meshheading:1803857-Gestational Age,
pubmed-meshheading:1803857-Humans,
pubmed-meshheading:1803857-Immunohistochemistry,
pubmed-meshheading:1803857-Isomerism,
pubmed-meshheading:1803857-Muscles,
pubmed-meshheading:1803857-Myosins,
pubmed-meshheading:1803857-Pregnancy
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pubmed:year |
1991
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pubmed:articleTitle |
Appearance and localization of dystrophin in normal human fetal muscle.
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pubmed:affiliation |
Centro Dino Ferrari, Università di Milano, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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