Linked Life Data

18036924

Source:http://linkedlifedata.com/resource/pubmed/id/18036924

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2007-11-26
pubmed:abstractText
Extracorporeal circulation used in cardiopulmonary bypass and hemodialysis is often associated with severe hypotension, which is an important predictor for mortality and morbidity. One pathophysiological hypothesis includes nitric oxide (NO) generation. Recently, a functional NO synthase (endothelial type NO synthase [eNOS]), was found to be expressed in human red blood cells. However, to date, activation of red blood cell eNOS has not been shown. We hypothesized that eNOS in circulating red blood cells might be activated during extracorporeal circulation and thus contribute to hypotension through vasodilation upon NO release.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1552-6259
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
84
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2000-3
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Extracorporeal circulation activates endothelial nitric oxide synthase in erythrocytes.
pubmed:affiliation
Michael E. DeBakey Institute, Texas A&M University, College Station, Texas, USA.
pubmed:publicationType
Journal Article