rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
2007-11-22
|
pubmed:abstractText |
P120-catenin is a member of the Armadillo protein family, which is involved in intercellular adhesion and cell signalling. It directly interacts with the classical cadherins juxtamembrane domain and contributes for both junction formation and its disassembly. Accumulating evidences indicate that p120-catenin is important in tumour formation and progression, although the role of their multiple spliced isoforms in the regulation of cadherin-mediated adhesion of malignant cells is still not well understood. We investigated the expression of p120-catenin isoforms in a collection of breast cancer cell lines with distinct molecular profiles and expressing different cadherins.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1570-5870
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
29
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
467-76
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:18032823-Blotting, Western,
pubmed-meshheading:18032823-Breast Neoplasms,
pubmed-meshheading:18032823-Cadherins,
pubmed-meshheading:18032823-Catenins,
pubmed-meshheading:18032823-Cell Adhesion Molecules,
pubmed-meshheading:18032823-Cell Line, Tumor,
pubmed-meshheading:18032823-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18032823-Humans,
pubmed-meshheading:18032823-Phenotype,
pubmed-meshheading:18032823-Phosphoproteins,
pubmed-meshheading:18032823-Protein Isoforms,
pubmed-meshheading:18032823-RNA, Messenger,
pubmed-meshheading:18032823-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18032823-Transcription, Genetic
|
pubmed:year |
2007
|
pubmed:articleTitle |
Expression of p120-catenin isoforms correlates with genomic and transcriptional phenotype of breast cancer cell lines.
|
pubmed:affiliation |
Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal. jparedes@ecsaude.uminho.pt
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|