Linked Life Data

18032471

Source:http://linkedlifedata.com/resource/pubmed/id/18032471

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-1-31
pubmed:abstractText
Djungarian or Siberian hamsters (Phodopus sungorus) acclimated to short photoperiod display episodes of spontaneous daily torpor with metabolic rate depressed by approximately 70% and body temperature (T(b)) reduced by approximately 20 degrees C. To study the cardiovascular adjustment to daily torpor in Phodopus, electrocardiogram (ECG) and T(b) were continuously recorded by telemetry during entrance into torpor, in deep torpor, and during arousal from torpor. Minimum T(b) during torpor bouts was approximately 21 degrees C, and heart rate, approximately 349 beats/min at euthermy, displayed marked sinus bradyarrhythmia at approximately 70 beats/min. Arousal was typically completed within approximately 40 min, followed by a sustained post-torpor inactivity tachycardia ( approximately 540 beats/min). The absence of episodes of conduction block, tachyarrhythmia, or other forms of ectopy throughout the torpor cycle demonstrates a remarkable resistance to arrhythmogenesis. The ECG morphology lacks a distinct isoelectric interval following the QRS complex, and the ST segment resembles the ECG pattern in mice, with a prominent fast transient outward K(+) current (I(to,f)) determining the early phase of ventricular repolarization. During low-temperature torpor, the amplitudes of the QRS complex substantially increased, suggesting that in the euthermic state the terminal portion of ventricular depolarization is fused with the beginning of repolarization, low T(b) acting to decorrelate the superposition between depolarization and repolarization by delaying the repolarization onset. Atrioventricular and ventricular conduction times were prolonged as function of T(b). In contrast, the QT vs. T(b) relationship showed marked hysteresis indicating the operation of nonlinear control mechanisms whereby the rapid QT shortening during arousal results from additional mechanisms (probably sympathetic stimulation) other than temperature alone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0363-6119
pubmed:author
pubmed:issnType
Print
pubmed:volume
294
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
R639-50
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Cardiac dynamics during daily torpor in the Djungarian hamster (Phodopus sungorus).
pubmed:affiliation
Fractal Physiology, Max Planck Institute for Experimental Medicine, Hermann Rein Strasse 3, Göttingen, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't