Linked Life Data

18032093

Source:http://linkedlifedata.com/resource/pubmed/id/18032093

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2007-12-6
pubmed:abstractText
Dictyostelium is one of the most successful and best-studied organisms for research into the mechanisms that drive chemotaxis. In this review, we discuss recent progress in the field. Phosphatidylinositol 3-kinase (PI 3-kinase), previously thought by some to be essential for chemotaxis, has now been proven to be dispensable. However, other pathways are emerging which might connect signalling to migration. In particular, phospholipase A2 homologues appear to play an important role. Other areas of current interest include the fundamental processes by which cells move - pseudopods have been found to be generated in many different ways. Similarly, chemotaxis may be mediated by multiple checks on the number of pseudopods, rather than by simple generation of new pseudopods on demand. Finally, we review several advances in the theory of how cells convert shallow, noisy chemical gradients into overt movement.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1369-5274
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
578-81
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Chemotaxis in Dictyostelium: how to walk straight using parallel pathways.
pubmed:affiliation
The Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, United Kingdom. r.insall@beatson.gla.ac.uk
pubmed:publicationType
Journal Article, Review