rdf:type |
|
lifeskim:mentions |
umls-concept:C0017337,
umls-concept:C0022702,
umls-concept:C0025266,
umls-concept:C0028754,
umls-concept:C0087111,
umls-concept:C0205419,
umls-concept:C0205666,
umls-concept:C0360714,
umls-concept:C0871261,
umls-concept:C1521761,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
pubmed:issue |
1
|
pubmed:dateCreated |
2008-7-7
|
pubmed:abstractText |
Niemann-Pick C1-like 1 protein (NPC1L1) plays a key role in lipoprotein metabolism. We examined the association of common genetic polymorphisms in NPC1L1 on apolipoprotein (apo) B-100 metabolism and the response to statin treatment in 37 men with central obesity.
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pubmed:grant |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Obesity Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoprotein B-100,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, VLDL,
http://linkedlifedata.com/resource/pubmed/chemical/Heptanoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl-CoA...,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/NPC1L1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles,
http://linkedlifedata.com/resource/pubmed/chemical/atorvastatin
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
pubmed:issn |
1365-2265
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pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
69
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
45-51
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pubmed:meshHeading |
pubmed-meshheading:18031309-Adult,
pubmed-meshheading:18031309-Anti-Obesity Agents,
pubmed-meshheading:18031309-Apolipoprotein B-100,
pubmed-meshheading:18031309-Cholesterol, VLDL,
pubmed-meshheading:18031309-Drug Resistance,
pubmed-meshheading:18031309-Genetic Variation,
pubmed-meshheading:18031309-Genotype,
pubmed-meshheading:18031309-Heptanoic Acids,
pubmed-meshheading:18031309-Humans,
pubmed-meshheading:18031309-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:18031309-Kinetics,
pubmed-meshheading:18031309-Male,
pubmed-meshheading:18031309-Membrane Proteins,
pubmed-meshheading:18031309-Middle Aged,
pubmed-meshheading:18031309-Obesity,
pubmed-meshheading:18031309-Pyrroles,
pubmed-meshheading:18031309-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
Variation in Niemann-Pick C1-like 1 gene as a determinant of apolipoprotein B-100 kinetics and response to statin therapy in centrally obese men.
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pubmed:affiliation |
Metabolic Research Centre, School of Medicine and Pharmacology, University of Western Australia, Perth, Australia.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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