Source:http://linkedlifedata.com/resource/pubmed/id/18029593
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
51
|
| pubmed:dateCreated |
2007-11-21
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| pubmed:abstractText |
The chemical structure of the mercury-mediated T-T pair (T-Hg(I)I-T) was determined with (15)N NMR spectroscopy. In order to determine the chemical structure of the T-Hg(I)I-T pair, (15)N-(15)N J-coupling across a metal center (2JNN) was employed. Notably, this is the first observation of (2)J(NN) in a biological macromolecule (DNA duplex). This pairing mode was found to be a irregular metal ion-binding mode for DNA and RNA molecules, in which imino proton-metal exchange processes are included. Accordingly, (2)J(NN) is highly important for the determination of the chemical structures of metal-mediated base pairs.
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| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1746-8272
|
| pubmed:author |
pubmed-author:BOERSGG,
pubmed-author:HarutaKaichiroK,
pubmed-author:KawamuraTakuyaT,
pubmed-author:KojimaChojiroC,
pubmed-author:KondoYoshinoriY,
pubmed-author:MiuraTakashiT,
pubmed-author:OdaShujiS,
pubmed-author:TakeuchiHideoH,
pubmed-author:TanakaYoshiyukiY,
pubmed-author:TorigoeHidetakaH,
pubmed-author:UchiyamaTomomiT,
pubmed-author:YamaguchiHiroshiH
|
| pubmed:issnType |
Electronic
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
75-6
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| pubmed:meshHeading | |
| pubmed:year |
2007
|
| pubmed:articleTitle |
Structural and physicochemical features on the metal-mediated base pairs.
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| pubmed:affiliation |
Graduate School of Pharmaceutical Sciences, Tohoku University, Aobayama, Aoba-ku, Sendai 980-8578, Japan. tanaka@mail.pharm.tohoku.ac.jp
|
| pubmed:publicationType |
Journal Article
|