rdf:type |
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lifeskim:mentions |
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pubmed:issue |
20
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pubmed:dateCreated |
2007-11-21
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pubmed:abstractText |
Chemotherapy is the most frequently adopted adjuvant therapy of pancreatic ductal adenocarcinoma (PDAC), but the development of drug resistance reduces its effectiveness. Clarification of the mechanism of multidrug resistance (MDR) development in PDAC is needed to improve the therapeutic effect of chemotherapy. This study was aimed to investigate the molecular mechanism of MDR of PDAC and to identify genes associated with MDR development.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cell Cycle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/GPX3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/GSTM4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Glutathione Peroxidase,
http://linkedlifedata.com/resource/pubmed/chemical/Glutathione Transferase,
http://linkedlifedata.com/resource/pubmed/chemical/HAUS1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Microtubule-Associated Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/TNKS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Tankyrases
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0366-6999
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
120
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1743-52
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pubmed:dateRevised |
2011-10-14
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pubmed:meshHeading |
pubmed-meshheading:18028764-Cell Cycle Proteins,
pubmed-meshheading:18028764-Cell Line, Tumor,
pubmed-meshheading:18028764-Computational Biology,
pubmed-meshheading:18028764-Drug Resistance, Multiple,
pubmed-meshheading:18028764-Drug Resistance, Neoplasm,
pubmed-meshheading:18028764-Gene Expression Profiling,
pubmed-meshheading:18028764-Glutathione Peroxidase,
pubmed-meshheading:18028764-Glutathione Transferase,
pubmed-meshheading:18028764-Humans,
pubmed-meshheading:18028764-Microtubule-Associated Proteins,
pubmed-meshheading:18028764-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:18028764-Pancreatic Neoplasms,
pubmed-meshheading:18028764-Tankyrases
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pubmed:year |
2007
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pubmed:articleTitle |
Microarray analysis of gene expression profile of multidrug resistance in pancreatic cancer.
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pubmed:affiliation |
Department of General Surgery, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing 100730, China. zhao8028@yahoo.com.cn
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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