|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2008-1-24
|
|
pubmed:abstractText |
The functional R620W (c.1858C>T) variant of the protein tyrosine phosphatase nonreceptor 22 gene (PTPN22) has been associated with a variety of autoimmune disorders. A recent study has suggested that R620W also contributes to the severe form of alopecia areata (AA).
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0007-0963
|
|
pubmed:author |
pubmed-author:BetzR CRC,
pubmed-author:BlaumeiserBB,
pubmed-author:De WeertJJ,
pubmed-author:EigelshovenSS,
pubmed-author:FlaquerAA,
pubmed-author:HannekenSS,
pubmed-author:HillmerAA,
pubmed-author:KönigKK,
pubmed-author:KortümA-KAK,
pubmed-author:LVOVAT NTN,
pubmed-author:LambertJJ,
pubmed-author:LutzGG,
pubmed-author:NöthenM MMM,
pubmed-author:RedlerSS,
pubmed-author:TütingTT
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
158
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
389-91
|
|
pubmed:meshHeading |
pubmed-meshheading:18028494-Adolescent,
pubmed-meshheading:18028494-Adult,
pubmed-meshheading:18028494-Aged,
pubmed-meshheading:18028494-Aged, 80 and over,
pubmed-meshheading:18028494-Alopecia Areata,
pubmed-meshheading:18028494-Belgium,
pubmed-meshheading:18028494-Case-Control Studies,
pubmed-meshheading:18028494-Child,
pubmed-meshheading:18028494-Child, Preschool,
pubmed-meshheading:18028494-Female,
pubmed-meshheading:18028494-Genetic Predisposition to Disease,
pubmed-meshheading:18028494-Germany,
pubmed-meshheading:18028494-Humans,
pubmed-meshheading:18028494-Male,
pubmed-meshheading:18028494-Middle Aged,
pubmed-meshheading:18028494-Polymorphism, Genetic,
pubmed-meshheading:18028494-Protein Tyrosine Phosphatase, Non-Receptor Type 22
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
The R620W polymorphism in PTPN22 confers general susceptibility for the development of alopecia areata.
|
|
pubmed:affiliation |
Institute of Human Genetics, University of Bonn, Wilhelmstrasse 31, D-53111 Bonn, Germany. regina.betz@uni-bonn.de
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
|
