Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-1-10
pubmed:abstractText
Nocturnal hypermotor seizures (NHSs) suggest seizure onset in the frontal lobe. We present a patient with NHSs and insular seizure onset who underwent successful surgical treatment. A 29-year-old right-handed man suffered from intractable NHSs since the age of 12 years. High-resolution MRI, [(18)F]FDG-PET, and neuropsychological examination gave normal results, ictal EEG was obscured by artifacts. Ictal [(99m)Tc]HMPAO-SPECT revealed hyperperfusion in the right anterior part of the insula and right frontal operculum. The seizure onset zone was localized in the right anterior insula based on invasive recordings. Electrical stimulation in that area elicited habitual seizures. A limited resection of the anterior part of the right insula and the right frontal operculum was performed rendering the patient seizure-free (follow-up 1 year). To our knowledge, this is the first reported nonlesional patient with an insular seizure onset and NHSs who underwent successful epilepsy surgery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0013-9580
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
159-62
pubmed:meshHeading
pubmed-meshheading:18028409-Adult, pubmed-meshheading:18028409-Cerebral Cortex, pubmed-meshheading:18028409-Disease-Free Survival, pubmed-meshheading:18028409-Electrodes, Implanted, pubmed-meshheading:18028409-Electroencephalography, pubmed-meshheading:18028409-Epilepsy, Frontal Lobe, pubmed-meshheading:18028409-Follow-Up Studies, pubmed-meshheading:18028409-Frontal Lobe, pubmed-meshheading:18028409-Functional Laterality, pubmed-meshheading:18028409-Humans, pubmed-meshheading:18028409-Magnetic Resonance Imaging, pubmed-meshheading:18028409-Male, pubmed-meshheading:18028409-Neurosurgical Procedures, pubmed-meshheading:18028409-Seizures, pubmed-meshheading:18028409-Sleep Disorders, pubmed-meshheading:18028409-Technetium Tc 99m Exametazime, pubmed-meshheading:18028409-Tomography, Emission-Computed, Single-Photon, pubmed-meshheading:18028409-Treatment Outcome
pubmed:year
2008
pubmed:articleTitle
Successful surgical treatment of insular epilepsy with nocturnal hypermotor seizures.
pubmed:affiliation
Department of Neurology, Innsbruck Medical University, Innsbruck, Austria.
pubmed:publicationType
Journal Article, Case Reports