Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-3-11
pubmed:abstractText
This paper reports on the largest series of pathological fractures of the mandible (n=44) in the literature, with the aim of proposing an aetiologic classification and algorithm for treatment. A retrospective review was undertaken of cases treated in the Department of Oral and Maxillofacial Surgery at the University of Maryland Medical Center from 1991 to 2005. Data collected included age, gender, race, aetiology, site, management and outcome. Forty-three patients with 44 pathologic fractures were included. The most common aetiology was osteoradionecrosis (49%), followed by infections (19%) and malignancy (19%). The most frequent primary treatment utilized was mandibular resection of diseased bone and fixation with a locking reconstruction plate alone (55%). Either primary or secondary mandibular reconstruction was performed when co-morbid disease allowed such treatment. Management of pathological fractures is aimed initially at systemic issues, followed by focusing on site-specific issues. This is a complex problem with a 40% complication rate, with radiation therapy associated with 59% of the complications. Free flap reconstruction should be considered when possible, especially in cases secondary to osteoradionecrosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0901-5027
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
215-22
pubmed:meshHeading
pubmed-meshheading:18023145-Adult, pubmed-meshheading:18023145-Aged, pubmed-meshheading:18023145-Aged, 80 and over, pubmed-meshheading:18023145-Algorithms, pubmed-meshheading:18023145-Bone Plates, pubmed-meshheading:18023145-Child, Preschool, pubmed-meshheading:18023145-Disease, pubmed-meshheading:18023145-Female, pubmed-meshheading:18023145-Follow-Up Studies, pubmed-meshheading:18023145-Fractures, Spontaneous, pubmed-meshheading:18023145-Humans, pubmed-meshheading:18023145-Male, pubmed-meshheading:18023145-Mandible, pubmed-meshheading:18023145-Mandibular Diseases, pubmed-meshheading:18023145-Mandibular Fractures, pubmed-meshheading:18023145-Mandibular Neoplasms, pubmed-meshheading:18023145-Middle Aged, pubmed-meshheading:18023145-Osteomyelitis, pubmed-meshheading:18023145-Osteoradionecrosis, pubmed-meshheading:18023145-Postoperative Complications, pubmed-meshheading:18023145-Reconstructive Surgical Procedures, pubmed-meshheading:18023145-Retrospective Studies, pubmed-meshheading:18023145-Treatment Outcome
pubmed:year
2008
pubmed:articleTitle
Treatment rationale for pathological fractures of the mandible: a series of 44 fractures.
pubmed:affiliation
University of Maryland Medical System, R Adam Cowley Shock Trauma Center, Baltimore, MD, USA. dcoletti@umm.edu
pubmed:publicationType
Journal Article