Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1992-4-21
pubmed:abstractText
The effect of stimulation frequency on the timecourse of neuromuscular blockade, following the administration of textilotoxin (20 micrograms/kg) or beta-bungarotoxin (50 micrograms/kg), was examined in the interdigital muscles of the hindlimb in anaesthetized mice. While the time of death was variable, neuromuscular blockade of the interdigital muscles occurred at the same time as respiratory failure with both textilotoxin and beta-bungarotoxin only at stimulation rates of 0.5 Hz and above. Textilotoxin (50 micrograms/kg) produced an increase in the heart rate prior to death but no change in the shape of the electrocardiogram.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0041-0101
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1266-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Frequency-dependent neuromuscular blockade by textilotoxin in vivo.
pubmed:affiliation
Department of Pharmacology, University of Sydney, NSW, Australia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't