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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2007-11-16
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pubmed:abstractText |
Severe malaria and one of its most important pathogenic processes, cerebral malaria, involves the sequestration of parasitized red blood cells (pRBCs) in brain postcapillary venules. Although the pathogenic mechanisms underlying malaria remain poorly characterized, it has been established that adhesion of pRBCs to endothelial cells (ECs) can result in cell apoptosis, which in turn may lead to disruption of the blood-brain barrier. The nature of the parasite molecules involved in the pathogenesis of severe malaria remains elusive.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0022-1899
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pubmed:author |
pubmed-author:BischoffEmmanuelE,
pubmed-author:BisserSylvieS,
pubmed-author:BisvigouUlrickU,
pubmed-author:CiceronLilianeL,
pubmed-author:CoppeeJean-YvesJY,
pubmed-author:DavidPeter HPH,
pubmed-author:FroissardPatrickP,
pubmed-author:MahmoudiNassiraN,
pubmed-author:MazierDominiqueD,
pubmed-author:Ouwe-Missi-Oukem-BoyerOdileO,
pubmed-author:SiauAnthonyA,
pubmed-author:ToureFousseyni SFS,
pubmed-author:VaqueroCatherineC
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
196
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1603-12
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pubmed:dateRevised |
2010-3-23
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pubmed:meshHeading |
pubmed-meshheading:18008243-Animals,
pubmed-meshheading:18008243-Apoptosis,
pubmed-meshheading:18008243-Blood-Brain Barrier,
pubmed-meshheading:18008243-Brain,
pubmed-meshheading:18008243-Cell Adhesion,
pubmed-meshheading:18008243-Child,
pubmed-meshheading:18008243-DNA, Protozoan,
pubmed-meshheading:18008243-Endothelial Cells,
pubmed-meshheading:18008243-Erythrocytes,
pubmed-meshheading:18008243-Gabon,
pubmed-meshheading:18008243-Gene Expression Profiling,
pubmed-meshheading:18008243-Genes, Protozoan,
pubmed-meshheading:18008243-Humans,
pubmed-meshheading:18008243-Malaria, Cerebral,
pubmed-meshheading:18008243-Malaria, Falciparum,
pubmed-meshheading:18008243-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:18008243-Plasmodium falciparum,
pubmed-meshheading:18008243-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18008243-Virulence Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Whole-transcriptome analysis of Plasmodium falciparum field isolates: identification of new pathogenicity factors.
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pubmed:affiliation |
Institut National de la Sante et de la Recherche Medicale U511, Paris 75013, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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