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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2007-12-6
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pubmed:abstractText |
The activation of the renin-angiotensin-aldosterone system prevents the uptake of norepinephrine in the myocardium. However, the additive effects of combined spironolactone and candesartan on cardiac sympathetic nerve activity (CSNA) have not been determined. We investigated the effects of the angiotensin-receptor blocker candesartan alone and in combination with spironolactone on CSNA in patients with congestive heart failure (CHF).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0161-5505
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1993-2000
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pubmed:meshHeading |
pubmed-meshheading:18006623-3-Iodobenzylguanidine,
pubmed-meshheading:18006623-Aged,
pubmed-meshheading:18006623-Angiotensin II Type 1 Receptor Blockers,
pubmed-meshheading:18006623-Benzimidazoles,
pubmed-meshheading:18006623-Blood Pressure,
pubmed-meshheading:18006623-Drug Synergism,
pubmed-meshheading:18006623-Echocardiography,
pubmed-meshheading:18006623-Female,
pubmed-meshheading:18006623-Heart,
pubmed-meshheading:18006623-Heart Failure,
pubmed-meshheading:18006623-Humans,
pubmed-meshheading:18006623-Male,
pubmed-meshheading:18006623-Middle Aged,
pubmed-meshheading:18006623-Natriuretic Peptide, Brain,
pubmed-meshheading:18006623-Spironolactone,
pubmed-meshheading:18006623-Sympathetic Nervous System,
pubmed-meshheading:18006623-Tetrazoles,
pubmed-meshheading:18006623-Ventricular Function, Left,
pubmed-meshheading:18006623-Ventricular Remodeling
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pubmed:year |
2007
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pubmed:articleTitle |
Additive effects of spironolactone and candesartan on cardiac sympathetic nerve activity and left ventricular remodeling in patients with congestive heart failure.
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pubmed:affiliation |
Department of Cardiovascular Medicine, Gunma University School of Medicine, Maebashi, Japan. s-kasama@bay.wind.ne.jp
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
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