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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-3
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pubmed:abstractText |
Transforming growth factor-beta1 (TGF-beta1) is a multifunctional cytokine that contributes to pathogenic cardiac remodelling via mechanisms that involve oxidative stress. However, the direct impact of TGF-beta1 on contractile function of ventricular myocytes is incompletely understood.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
77
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
107-17
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pubmed:meshHeading |
pubmed-meshheading:18006470-Animals,
pubmed-meshheading:18006470-Calcium,
pubmed-meshheading:18006470-Glutathione,
pubmed-meshheading:18006470-Myocardial Contraction,
pubmed-meshheading:18006470-Myocytes, Cardiac,
pubmed-meshheading:18006470-NADPH Oxidase,
pubmed-meshheading:18006470-Oxidative Stress,
pubmed-meshheading:18006470-Rats,
pubmed-meshheading:18006470-Reactive Oxygen Species,
pubmed-meshheading:18006470-Sarcoplasmic Reticulum Calcium-Transporting ATPases,
pubmed-meshheading:18006470-Transforming Growth Factor beta1,
pubmed-meshheading:18006470-Ventricular Function
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pubmed:year |
2008
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pubmed:articleTitle |
Pro-oxidant effect of transforming growth factor- beta1 mediates contractile dysfunction in rat ventricular myocytes.
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pubmed:affiliation |
Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, 985850 Nebraska Medical Center, Omaha, NE 68198-5850, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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