Source:http://linkedlifedata.com/resource/pubmed/id/18005187
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2007-12-14
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| pubmed:abstractText |
A systematic review (SR) is the unbiased appraisal of systematically identified relevant studies. Implicit in its definition is a robust and scientifically valid process, and when performed as such, SR is an important clinical research tool and influence in health policy decision-making. This educational paper outlines that, from the original prototype based on randomized trials, there are now many other types of SRs including those based on: nonrandomized comparative studies, observational studies, prognostic studies, and studies of diagnostic and screening tools. While each of these has a similar 'anatomy' or format, at an individual class level, there are principles specific to each SR type. Several examples from the coloproctology literature are used as case-studies to illustrate potential pitfalls, and upon re-analysis, often reverse or attenuate the conclusions stated in the original publication. These examples serve to emphasize the need for health professionals to understand the process of SR and meta-analysis so that we all arrive at appropriate interpretations to the benefit of our patients.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
1463-1318
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| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
10
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
21-32
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| pubmed:meshHeading |
pubmed-meshheading:18005187-Colectomy,
pubmed-meshheading:18005187-Colorectal Neoplasms,
pubmed-meshheading:18005187-Colorectal Surgery,
pubmed-meshheading:18005187-Controlled Clinical Trials as Topic,
pubmed-meshheading:18005187-Epidemiologic Studies,
pubmed-meshheading:18005187-Female,
pubmed-meshheading:18005187-Great Britain,
pubmed-meshheading:18005187-Humans,
pubmed-meshheading:18005187-Male,
pubmed-meshheading:18005187-Meta-Analysis as Topic,
pubmed-meshheading:18005187-Proctocolectomy, Restorative,
pubmed-meshheading:18005187-Randomized Controlled Trials as Topic,
pubmed-meshheading:18005187-Review Literature as Topic,
pubmed-meshheading:18005187-Risk Assessment,
pubmed-meshheading:18005187-Sensitivity and Specificity,
pubmed-meshheading:18005187-Survival Analysis,
pubmed-meshheading:18005187-Treatment Outcome
|
| pubmed:year |
2008
|
| pubmed:articleTitle |
Systematic reviews and meta-analyses in coloproctology: interpretation and potential pitfalls.
|
| pubmed:affiliation |
Department of Surgery K, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark. pwj01@bbh.regionh.dk
|
| pubmed:publicationType |
Journal Article,
Review,
Meta-Analysis
|