Source:http://linkedlifedata.com/resource/pubmed/id/18003392
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2007-11-16
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pubmed:abstractText |
This paper reports on technology development at the sensor and circuit levels for wireless transmission of fast-scan cyclic voltammetry (FSCV) in neurochemical detection. Heavily conductive, boron-doped diamond is selectively deposited onto the polished tip of a tungsten microelectrode to fabricate versatile, implantable, micro-needle microprobes capable of neurochemical sensing in the brain. In addition, an integrated circuit is fabricated in a 0.5-microm CMOS technology for processing and wireless transmission of the electrochemical signals corresponding to extracellular concentration changes of various neurotransmitters. The chip consists of a current-based, second-order, front-end SigmaDelta ADC and an on-chip, RF-FSK transmitter at the back-end. The ADC core and the transmitter consume 22microA and 400microA, respectively, from a 2.6-V power supply. Major electroactive neurotransmitters such as serotonin and dopamine in micromolar concentration have been wirelessly recorded at 433MHz using 300-V/s FSCV in flow injection analysis experiments.
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pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/1 R01 EB004018-01 A2,
http://linkedlifedata.com/resource/pubmed/grant/R01 NS047073-01A2,
http://linkedlifedata.com/resource/pubmed/grant/R01 NS047073-02,
http://linkedlifedata.com/resource/pubmed/grant/R01 NS047073-03,
http://linkedlifedata.com/resource/pubmed/grant/R01 NS047073-04
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1557-170X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
2007
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6044-7
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pubmed:dateRevised |
2011-4-22
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pubmed:meshHeading |
pubmed-meshheading:18003392-Diamond,
pubmed-meshheading:18003392-Electrochemistry,
pubmed-meshheading:18003392-Electronics,
pubmed-meshheading:18003392-Equipment Design,
pubmed-meshheading:18003392-Equipment Failure Analysis,
pubmed-meshheading:18003392-Microelectrodes,
pubmed-meshheading:18003392-Miniaturization,
pubmed-meshheading:18003392-Neurotransmitter Agents,
pubmed-meshheading:18003392-Semiconductors,
pubmed-meshheading:18003392-Serotonin,
pubmed-meshheading:18003392-Telemetry
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pubmed:year |
2007
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pubmed:articleTitle |
Diamond microelectrodes and CMOS microelectronics for wireless transmission of fast-scan cyclic voltammetry.
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pubmed:affiliation |
Electrical Engineering and Computer Science Department, Case Western Reserve University, Cleveland, OH 44106, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies,
Research Support, N.I.H., Extramural
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