Linked Life Data

1799871

Source:http://linkedlifedata.com/resource/pubmed/id/1799871

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1992-4-21
pubmed:abstractText
Correlative light and electron microscopic immunocytochemical methods were used to study the pattern of staining for the calcium-binding protein parvalbumin (PV) in the primary visual area (area 17) and area 3b of the first somatic sensory area of the monkey cerebral cortex. A conspicuous feature of the light microscopic staining pattern is the presence of focal aggregations of immunoreactive terminal-like puncta within the major thalamic recipient layers (IV and VI). At the electron microscopic level these aggregations of puncta are found to be immunoreactive terminals most of which form asymmetric synapses, principally on dendritic spines and, to a lesser extent, on dendritic shafts. Outside the aggregations, most PV-immunoreactive terminals form symmetric synapses. Correlative observations in the present and other studies indicate that the aggregations of PV-immunoreactive terminals forming asymmetric synapses arise from thalamic afferent fibers while those forming symmetric synapses arise from intrinsic gamma-aminobutyric acid neurons. The aggregations of PV immunoreactivity in layers IV and VI form microzones of preferred thalamic afferent terminations which may contribute to the formation of functional columns based upon focussed thalamic inputs.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
18
pubmed:volume
562
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
39-47
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Parvalbumin immunoreactivity reveals layer IV of monkey cerebral cortex as a mosaic of microzones of thalamic afferent terminations.
pubmed:affiliation
Department of Anatomy and Neurobiology, University of California, Irvine 92717.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.