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| pubmed-article:17996973 | lifeskim:mentions | umls-concept:C0039260 | lld:lifeskim |
| pubmed-article:17996973 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:17996973 | pubmed:dateCreated | 2008-2-4 | lld:pubmed |
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| pubmed-article:17996973 | pubmed:abstractText | Influenza B viruses were predominant in Taiwan during the 2004-2005 epidemic and both Victoria and Yamagata lineage viruses co-circulated. A reassortant influenza B virus that contained a Victoria lineage hemagglutinin (HA) gene and Yamagata lineage neuraminidase (NA) gene appeared first in 2002 and became predominant during the 2004-2005 epidemic. During the 2006-2007 epidemic, an influenza B outbreak occurred in Taiwan and only Victoria lineage viruses circulated. We characterized the viruses isolated in the 2006-2007 epidemic and found that the HA genes of influenza B viruses from that epidemic were highly similar to those from the 2004-2005 epidemic. We also analyzed the NA genes of isolates from the 2006-2007 epidemic and found that they all belonged to the Yamagata lineage and formed a new genetic subclade. Comparison of isolates from the 2004-2005 and 2006-2007 epidemics revealed four substitutions, N220K, E320D, K343R and E404K in NA genes. Although the HA sequences from the 2006-2007 epidemic were similar to those from the 2004-2005 epidemic, the NA sequences differed, suggesting distinct patterns of evolution of the HA and NA genes from 2004-2007 in Taiwan. This study emphasizes that the evolution of the NA genes may contribute to reemergence of influenza B viruses. | lld:pubmed |
| pubmed-article:17996973 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17996973 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17996973 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17996973 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17996973 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:17996973 | pubmed:issn | 0168-1702 | lld:pubmed |
| pubmed-article:17996973 | pubmed:author | pubmed-author:ChenPei-JerPJ | lld:pubmed |
| pubmed-article:17996973 | pubmed:author | pubmed-author:LiuMing-TsanM... | lld:pubmed |
| pubmed-article:17996973 | pubmed:author | pubmed-author:WuHo-ShengHS | lld:pubmed |
| pubmed-article:17996973 | pubmed:author | pubmed-author:HsuLi-ChingLC | lld:pubmed |
| pubmed-article:17996973 | pubmed:author | pubmed-author:KuoSteve... | lld:pubmed |
| pubmed-article:17996973 | pubmed:author | pubmed-author:LaiCheng-Tsun... | lld:pubmed |
| pubmed-article:17996973 | pubmed:author | pubmed-author:JianJhih-WeiJ... | lld:pubmed |
| pubmed-article:17996973 | pubmed:author | pubmed-author:KuoChuan-YiCY | lld:pubmed |
| pubmed-article:17996973 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17996973 | pubmed:volume | 131 | lld:pubmed |
| pubmed-article:17996973 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17996973 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17996973 | pubmed:pagination | 243-9 | lld:pubmed |
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| pubmed-article:17996973 | pubmed:meshHeading | pubmed-meshheading:17996973... | lld:pubmed |
| pubmed-article:17996973 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:17996973 | pubmed:articleTitle | Genetic analysis and evaluation of the reassortment of influenza B viruses isolated in Taiwan during the 2004-2005 and 2006-2007 epidemics. | lld:pubmed |
| pubmed-article:17996973 | pubmed:affiliation | National Influenza Center, Centers for Disease Control, Taipei, Taiwan, ROC. | lld:pubmed |
| pubmed-article:17996973 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17996973 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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