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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-3-12
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pubmed:abstractText |
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: * Genetic polymorphisms of the P2Y(12) ADP receptor on platelets have been shown to contribute to variability in platelet aggregation in healthy humans. * P2Y(12) ADP receptor polymorphisms are more frequently present in patients with vascular disease than in healthy people. * The majority of patients with vascular disease receive acetylsalicylic acid as an anti-aggregatory agent, which has also been shown to induce a variable response; however, the role of P2Y(12) ADP receptor polymorphisms in the platelet response to acetylsalicylic acid in patients with vascular disease has not yet been studied.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-10506165,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-11196645,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-11425767,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-11566191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-11756171,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-12487788,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-12578987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-12912815,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-14056485,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-14662702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-15514209,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-15634270,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-15933261,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-16181985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-16194207,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-16364973,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-16460446,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-16488805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-17452618,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995973-9442039
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1365-2125
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
540-7
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pubmed:dateRevised |
2011-1-11
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pubmed:meshHeading |
pubmed-meshheading:17995973-Aged,
pubmed-meshheading:17995973-Aspirin,
pubmed-meshheading:17995973-Coronary Artery Disease,
pubmed-meshheading:17995973-Dose-Response Relationship, Drug,
pubmed-meshheading:17995973-Female,
pubmed-meshheading:17995973-Genotype,
pubmed-meshheading:17995973-Haplotypes,
pubmed-meshheading:17995973-Humans,
pubmed-meshheading:17995973-Male,
pubmed-meshheading:17995973-Platelet Activation,
pubmed-meshheading:17995973-Platelet Aggregation,
pubmed-meshheading:17995973-Platelet Aggregation Inhibitors,
pubmed-meshheading:17995973-Polymorphism, Genetic,
pubmed-meshheading:17995973-Receptors, Purinergic P2,
pubmed-meshheading:17995973-Receptors, Purinergic P2Y12,
pubmed-meshheading:17995973-Ticlopidine,
pubmed-meshheading:17995973-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
P2Y12 polymorphisms and antiplatelet effects of aspirin in patients with coronary artery disease.
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pubmed:affiliation |
Institute of Experimental and Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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