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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-3-12
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pubmed:abstractText |
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: * Two recent papers have been published which have attempted to build a full population pharmacokinetic model for tobramycin in children with cystic fibrosis. * However, neither study was able to provide any information about between-subject variability (BSV) and between-occasion variability (BOV), which is necessary to justify and draw conclusions about the use of target concentration intervention (TCI). * In the publications no simulations were provided to show any new directions or evaluate current therapy.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-10092956,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-10383541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-10383553,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-11106223,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-12222541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-12244003,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-1244564,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-15206987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-15521900,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-15708100,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-16176118,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-16829216,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-16972966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-17276147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-1860329,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-330081,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-3540140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-6364908,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-6385693,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-7654477,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-7846756,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-8743333,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-9131944,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-9357390,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17995972-9764963
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1365-2125
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
502-10
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pubmed:dateRevised |
2011-1-11
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pubmed:meshHeading |
pubmed-meshheading:17995972-Adolescent,
pubmed-meshheading:17995972-Anti-Bacterial Agents,
pubmed-meshheading:17995972-Body Weight,
pubmed-meshheading:17995972-Child,
pubmed-meshheading:17995972-Child, Preschool,
pubmed-meshheading:17995972-Cystic Fibrosis,
pubmed-meshheading:17995972-Dose-Response Relationship, Drug,
pubmed-meshheading:17995972-Drug Administration Schedule,
pubmed-meshheading:17995972-Female,
pubmed-meshheading:17995972-Humans,
pubmed-meshheading:17995972-Infant,
pubmed-meshheading:17995972-Injections, Intravenous,
pubmed-meshheading:17995972-Male,
pubmed-meshheading:17995972-Models, Chemical,
pubmed-meshheading:17995972-Predictive Value of Tests,
pubmed-meshheading:17995972-Retrospective Studies,
pubmed-meshheading:17995972-Tobramycin,
pubmed-meshheading:17995972-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
Target concentration intervention is needed for tobramycin dosing in paediatric patients with cystic fibrosis--a population pharmacokinetic study.
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pubmed:affiliation |
School of Pharmacy, The University of Queensland, Brisbane, Australia.
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pubmed:publicationType |
Journal Article
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