rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
2007-11-30
|
pubmed:abstractText |
Adipocytes secrete signalling molecules that elicit responses from target cells, including pancreatic beta cells. Wnt signalling molecules have recently been identified as novel adipocyte-derived factors. They also regulate insulin secretion in pancreatic beta cells and the cell cycle. The aim of this study was to investigate the effect of adipocyte-derived Wnt signalling molecules on insulin secretion and beta cell proliferation.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Jan
|
pubmed:issn |
0012-186X
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
51
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
147-54
|
pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17994217-Adipocytes,
pubmed-meshheading:17994217-Adult,
pubmed-meshheading:17994217-Animals,
pubmed-meshheading:17994217-Cell Proliferation,
pubmed-meshheading:17994217-Culture Media, Conditioned,
pubmed-meshheading:17994217-Female,
pubmed-meshheading:17994217-Glucokinase,
pubmed-meshheading:17994217-Humans,
pubmed-meshheading:17994217-Insulin,
pubmed-meshheading:17994217-Insulin-Secreting Cells,
pubmed-meshheading:17994217-Mice,
pubmed-meshheading:17994217-Mice, Inbred C57BL,
pubmed-meshheading:17994217-PPAR gamma,
pubmed-meshheading:17994217-Rats,
pubmed-meshheading:17994217-Transcription, Genetic,
pubmed-meshheading:17994217-Wnt Proteins
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pubmed:year |
2008
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pubmed:articleTitle |
Regulation of insulin secretion, glucokinase gene transcription and beta cell proliferation by adipocyte-derived Wnt signalling molecules.
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pubmed:affiliation |
Department of Endocrinology, Diabetes and Rheumatology, University Hospital Düsseldorf, Moorenstr. 5, 40225, Dusseldorf, Germany. sven.schinner@uni-duesseldorf.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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