Linked Life Data

17991257

Source:http://linkedlifedata.com/resource/pubmed/id/17991257

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2007-11-9
pubmed:abstractText
Seventy-two patients undergoing routine surgical procedures under propofol-remifentanil anaesthesia were randomly assigned to receive either standard clinical practice (n = 35) or standard practice plus monitoring of depth of anaesthesia with M-Entropy (n = 37). Patients in the standard practice group received more propofol than the entropy group (mean (SD) 95 (14) vs 81 (22) microg.kg(-1).min(-1), respectively; p < 0.01), and less remifentanil (0.39 (0.08) vs 0.46 (0.08) microg.kg(-1).min(-1), respectively; p < 0.001). Loss of consciousness was best predicted by BIS (prediction probability (P(K)) 0.96) and response entropy (P(K) 0.93), whereas emergence was best predicted by response entropy (P(K) 0.94). The frequency of unwanted patient responses was higher in the standard practice group than in the entropy group (47 vs 27 total events, respectively; p < 0.01). Both regimens resulted in fast recovery with no clinical advantage for either one. There were no significant differences in haemodynamic parameters, postoperative nausea and vomiting or satisfaction with the procedure.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1365-2044
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1224-9
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
M-Entropy guidance vs standard practice during propofol-remifentanil anaesthesia: a randomised controlled trial.
pubmed:affiliation
Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany. gruenewald@anaesthesie.uni-kiel.de
pubmed:publicationType
Journal Article, Randomized Controlled Trial