Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2007-11-9
pubmed:abstractText
The risk of death is nearly 45% lower in African-Americans than Caucasians undergoing chronic hemodialysis. In light of the higher mortality rate in African-Americans in the general US population, this paradox requires explanation and further investigation. Factors that may contribute to this survival advantage include a younger age at which African-Americans arrive at end-stage renal disease (ESRD) and the slightly higher body mass index. On the other hand, factors, such as lower residual renal function, lower mean hemoglobin and hematocrit, increased prevalence of hypertension, a higher prevalence of catheter use for initial dialysis, and generally lower dose of dialysis should put African-Americans on dialysis at a higher risk of death. This survival advantage seems to be completely annulled with a successful renal transplant. Finally, it should be noted that ESRD carries with it a very high mortality rate in all racial and ethnic groups. A successful renal transplant improves but does not restore the expected remaining life times. Therefore, aggressive approach is required in investigating the factors that confer such high mortality risk on ESRD patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0894-0959
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
577-85
pubmed:meshHeading
pubmed-meshheading:17991208-AIDS-Associated Nephropathy, pubmed-meshheading:17991208-African Americans, pubmed-meshheading:17991208-Age Factors, pubmed-meshheading:17991208-Aged, pubmed-meshheading:17991208-Diabetic Nephropathies, pubmed-meshheading:17991208-European Continental Ancestry Group, pubmed-meshheading:17991208-Female, pubmed-meshheading:17991208-Glomerulonephritis, pubmed-meshheading:17991208-Humans, pubmed-meshheading:17991208-Hypertension, pubmed-meshheading:17991208-Kidney Failure, Chronic, pubmed-meshheading:17991208-Kidney Transplantation, pubmed-meshheading:17991208-Male, pubmed-meshheading:17991208-Middle Aged, pubmed-meshheading:17991208-Morbidity, pubmed-meshheading:17991208-Nutritional Status, pubmed-meshheading:17991208-Peritoneal Dialysis, pubmed-meshheading:17991208-Renal Dialysis, pubmed-meshheading:17991208-Risk Factors, pubmed-meshheading:17991208-Survival Rate
pubmed:articleTitle
Racial and ethnic disparities in end-stage kidney failure-survival paradoxes in African-Americans.
pubmed:affiliation
National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA. agodoal@mail.nih.gov
pubmed:publicationType
Journal Article, Comparative Study, Review