Linked Life Data

17986892

Source:http://linkedlifedata.com/resource/pubmed/id/17986892

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2007-11-7
pubmed:abstractText
A 49-year-old patient sustained an ipsilateral fracture of the lateral femoral neck and distal femoral shaft, which were treated with a long intramedullary nail with a hip screw component. Both fractures did not heal, and both nonunion sites were revised by reosteosynthesis with a dynamic hip screw for the femoral neck and a locked intramedullary nail for the shaft region combined with autogenous bone grafting at both sites. At 14 months from injury and after 2 operations, both nonunions persisted. At a third surgery, 1 kit of recombinant human bone morphogenetic protein-2 (rhBMP-2) on an absorbable collagen sponge was applied to each site, without any modification of the osteosynthesis or additional bone grafting. The lateral femoral neck and the femoral shaft consolidated 24 and 30 weeks, respectively, after the rhBMP-2 application, and the patient resumed his work as industrial worker after 7 months after his last surgery. We believe this is the first study to report the successful use of 2 kits of rhBMP-2 in a double nonunion of the femur.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0890-5339
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
734-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:articleTitle
Treatment of a double nonunion of the femur by rhBMP-2.
pubmed:affiliation
Department of Trauma Surgery, University Hospital Giessen-Marburg, Site Giessen, Giessen, Germany. volker.alt@chiru.med.uni-giessen.de
pubmed:publicationType
Journal Article, Case Reports, Research Support, Non-U.S. Gov't