Source:http://linkedlifedata.com/resource/pubmed/id/17983844
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2008-2-26
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pubmed:abstractText |
Previous studies documenting the osteoconductive nature of calcium sulfate (CaSO(4))-based biomaterials have been largely limited to animal models exhibiting nonosteoporotic bone biology. In addition to diminished bone mineral density (BMD) and altered bone microarchitecture, the osteoporosis phenotype is associated with a proinflammatory and pro-osteolytic state. Thus, osteoporosis may elicit an amplified bioreactivity to common orthopedic biomaterials, potentially limiting their full osteoconductive capabilities in vivo.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1529-9430
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
340-50
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pubmed:meshHeading |
pubmed-meshheading:17983844-Animals,
pubmed-meshheading:17983844-Bone Cements,
pubmed-meshheading:17983844-Bone Density,
pubmed-meshheading:17983844-Calcium Sulfate,
pubmed-meshheading:17983844-Disease Models, Animal,
pubmed-meshheading:17983844-Female,
pubmed-meshheading:17983844-Injections, Intralesional,
pubmed-meshheading:17983844-Osteoporosis,
pubmed-meshheading:17983844-Rats,
pubmed-meshheading:17983844-Rats, Sprague-Dawley,
pubmed-meshheading:17983844-Spine
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pubmed:articleTitle |
Altered bioreactivity and limited osteoconductivity of calcium sulfate-based bone cements in the osteoporotic rat spine.
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pubmed:affiliation |
Department of Orthopedic Surgery, University of California, 200 West Arbor Drive MC 8894, San Diego, CA 92103, USA.
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pubmed:publicationType |
Journal Article
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