Source:http://linkedlifedata.com/resource/pubmed/id/17981032
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2008-1-9
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pubmed:abstractText |
A novel series of trisubstituted benzimidazole and its precursors (3-7) were synthesised and characterized by using 1H NMR, LC/MS, FTIR and elemental analysis techniques. The title compounds were evaluated for inhibition against MDA-MB-231 breast cancer cell proliferation. The results revealed that the compound N-(4-cyano-3-(trifluoromethyl) phenyl)-4-fluoro-3-nitrobenzamide (3) was the potent inhibitor.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1464-3405
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
432-5
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pubmed:meshHeading |
pubmed-meshheading:17981032-Antineoplastic Agents,
pubmed-meshheading:17981032-Benzimidazoles,
pubmed-meshheading:17981032-Breast Neoplasms,
pubmed-meshheading:17981032-Cell Growth Processes,
pubmed-meshheading:17981032-Cell Line, Tumor,
pubmed-meshheading:17981032-Humans,
pubmed-meshheading:17981032-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:17981032-Spectroscopy, Fourier Transform Infrared
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pubmed:year |
2008
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pubmed:articleTitle |
Synthesis, characterization and evaluation of benzimidazole derivative and its precursors as inhibitors of MDA-MB-231 human breast cancer cell proliferation.
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pubmed:affiliation |
Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore 570006, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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