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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2007-11-5
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pubmed:abstractText |
Radioimmunotherapy with anti-CD20 antibodies (Abs) labeled with beta-emitters is now used in the treatment of non-Hodgkin's lymphoma (NHL). Because (90)Y is a pure beta-emitter, no direct image of its distribution can be obtained in humans. In this paper, we present in this study imaging data of (90)Y-Ab distribution in human-mantle-cell lymphoma within a mouse model. Describing the actual distribution of the radionuclide at the level of particles range may have important impact on patient dosimetry and therapy treatment planning.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1084-9785
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
665-71
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17979569-Animals,
pubmed-meshheading:17979569-Antibodies, Monoclonal,
pubmed-meshheading:17979569-Antigens, CD45,
pubmed-meshheading:17979569-Autoradiography,
pubmed-meshheading:17979569-Binding Sites, Antibody,
pubmed-meshheading:17979569-Bone Marrow,
pubmed-meshheading:17979569-Cell Line, Tumor,
pubmed-meshheading:17979569-Femur,
pubmed-meshheading:17979569-Humans,
pubmed-meshheading:17979569-Immunoglobulin G,
pubmed-meshheading:17979569-Immunohistochemistry,
pubmed-meshheading:17979569-Immunotoxins,
pubmed-meshheading:17979569-Lymphoma, Mantle-Cell,
pubmed-meshheading:17979569-Lymphoma, Non-Hodgkin,
pubmed-meshheading:17979569-Mice,
pubmed-meshheading:17979569-Mice, Inbred NOD,
pubmed-meshheading:17979569-Mice, SCID,
pubmed-meshheading:17979569-Neprilysin,
pubmed-meshheading:17979569-Radioimmunotherapy,
pubmed-meshheading:17979569-Tissue Distribution,
pubmed-meshheading:17979569-Xenograft Model Antitumor Assays
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pubmed:year |
2007
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pubmed:articleTitle |
Imaging of the distribution of (90)y-ibritumomab tiuxetan in bone marrow and comparison with pathology.
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pubmed:affiliation |
Department of Physics, Institut Gustave-Roussy, Villejuif, France.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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