rdf:type |
|
lifeskim:mentions |
umls-concept:C0007600,
umls-concept:C0079419,
umls-concept:C0178539,
umls-concept:C0311400,
umls-concept:C0871261,
umls-concept:C1280500,
umls-concept:C1553877,
umls-concept:C1608885,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1707455,
umls-concept:C1880274,
umls-concept:C2911692
|
pubmed:issue |
5
|
pubmed:dateCreated |
2007-11-5
|
pubmed:abstractText |
The tumor suppressor gene, p53, plays a pivotal role for cell survival and apoptosis, which could cause different responses to therapeutic agents. Rhenium-188 ((188)Re) decays with the emission of a beta-particle with high energy and is expected to be an important candidate of radiotherapy. We investigated the cellular response of (18)F-fluorodeoxyglucose ((18)F-FDG) uptake and the effect of p53 according to beta-irradiation by (188)Re.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1084-9785
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
636-43
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:17979566-Beta Particles,
pubmed-meshheading:17979566-Cell Cycle,
pubmed-meshheading:17979566-Cell Survival,
pubmed-meshheading:17979566-Fluorodeoxyglucose F18,
pubmed-meshheading:17979566-Gamma Rays,
pubmed-meshheading:17979566-Gene Deletion,
pubmed-meshheading:17979566-HCT116 Cells,
pubmed-meshheading:17979566-Hexokinase,
pubmed-meshheading:17979566-Humans,
pubmed-meshheading:17979566-Metabolism,
pubmed-meshheading:17979566-Radioisotopes,
pubmed-meshheading:17979566-Rhenium,
pubmed-meshheading:17979566-Tumor Suppressor Protein p53
|
pubmed:year |
2007
|
pubmed:articleTitle |
Comparison of cellular metabolic responses of (18)F-FDG according to the effect of beta-irradiation in p53 wild and deleted cell lines.
|
pubmed:affiliation |
Laboratory of Nuclear Medicine Research, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|