Linked Life Data

17978854

Source:http://linkedlifedata.com/resource/pubmed/id/17978854

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2007-11-23
pubmed:abstractText
EMT (epithelial-mesenchymal transition) is a morphogenetic process in which cells loose their epithelial characteristics and gain mesenchymal properties during embryogenesis. Similar processes regulated by similar pathways are recapitulated during tumour progression, endowing cells with invasive properties, thereby contributing to the formation of metastases. In this review, we outline key features of EMT and discuss the evidence for its involvement in the dissemination of tumours. Finally we review the recent literature concerning the mechanisms that regulate EMT in the tumour context, with a particular focus on breast cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0262-0898
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
587-97
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer.
pubmed:affiliation
Department for Molecular Biomedical Research, Molecular and Cellular Oncology, VIB, Technologiepark 927, 9052, Ghent (Zwijnaarde), Belgium.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't