Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-11-5
pubmed:abstractText
Glucose should not be considered uniquely as a cellular fuel but also as a signaling molecule involved in the regulation of genes encoding glycolytic and lipogenic enzymes and, as such, in storage of triglycerides. Transcriptional effects of glucose on glycolytic and lipogenic enzymes involve a specific transcription factor, ChREBP, whose characteristics and mechanism of activation are described. Finally, the possible implication of ChREBP in the physiopathology of obesity and type 2 diabetes are discussed.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1295-0661
pubmed:author
pubmed:issnType
Print
pubmed:volume
201
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
159-64
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
[The regulation of gene expression by glucose].
pubmed:affiliation
INSERM U567, CNRS UMR 8104, Université Paris Descartes, Département d'Endocrinologie, Métabolisme et Cancer, Faculté de Médecine Cochin, 24, rue du Faubourg Saint-Jacques, 75014 Paris. girard@cochin.inserm.fr
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't