Source:http://linkedlifedata.com/resource/pubmed/id/17978749
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2007-11-5
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pubmed:abstractText |
Glucose should not be considered uniquely as a cellular fuel but also as a signaling molecule involved in the regulation of genes encoding glycolytic and lipogenic enzymes and, as such, in storage of triglycerides. Transcriptional effects of glucose on glycolytic and lipogenic enzymes involve a specific transcription factor, ChREBP, whose characteristics and mechanism of activation are described. Finally, the possible implication of ChREBP in the physiopathology of obesity and type 2 diabetes are discussed.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1295-0661
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
201
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
159-64
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pubmed:meshHeading |
pubmed-meshheading:17978749-Gene Expression Regulation,
pubmed-meshheading:17978749-Glucose,
pubmed-meshheading:17978749-Glycolysis,
pubmed-meshheading:17978749-Humans,
pubmed-meshheading:17978749-Lipids,
pubmed-meshheading:17978749-Signal Transduction,
pubmed-meshheading:17978749-Transcription, Genetic,
pubmed-meshheading:17978749-Transcription Factors,
pubmed-meshheading:17978749-Triglycerides
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pubmed:year |
2007
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pubmed:articleTitle |
[The regulation of gene expression by glucose].
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pubmed:affiliation |
INSERM U567, CNRS UMR 8104, Université Paris Descartes, Département d'Endocrinologie, Métabolisme et Cancer, Faculté de Médecine Cochin, 24, rue du Faubourg Saint-Jacques, 75014 Paris. girard@cochin.inserm.fr
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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