Source:http://linkedlifedata.com/resource/pubmed/id/17976454
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2007-11-2
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pubmed:abstractText |
Although deep hypothermic circulatory arrest has been known to induce neuronal injury, the molecular mechanism of this damage has not been identified. We studied the key molecular mediators through cellular energy failure, excitotoxicity, and overactivation of poly(adenosine diphosphate-ribose) polymerase 1 in brain tissues of a rabbit model of deep hypothermic circulatory arrest similar to clinical settings.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1097-685X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
134
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1227-33
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pubmed:meshHeading |
pubmed-meshheading:17976454-Animals,
pubmed-meshheading:17976454-Apoptosis,
pubmed-meshheading:17976454-Brain,
pubmed-meshheading:17976454-Brain Chemistry,
pubmed-meshheading:17976454-Brain Diseases,
pubmed-meshheading:17976454-Cardiopulmonary Bypass,
pubmed-meshheading:17976454-Circulatory Arrest, Deep Hypothermia Induced,
pubmed-meshheading:17976454-Disease Models, Animal,
pubmed-meshheading:17976454-Male,
pubmed-meshheading:17976454-Microdialysis,
pubmed-meshheading:17976454-Necrosis,
pubmed-meshheading:17976454-Neurons,
pubmed-meshheading:17976454-Poly(ADP-ribose) Polymerases,
pubmed-meshheading:17976454-Rabbits
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pubmed:year |
2007
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pubmed:articleTitle |
Overactivation of poly(adenosine phosphate-ribose) polymerase 1 and molecular events in neuronal injury after deep hypothermic circulatory arrest: study in a rabbit model.
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pubmed:affiliation |
Department of Cardiovascular Surgery and Aortic Surgery Center, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Peking, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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