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rdf:type |
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lifeskim:mentions |
umls-concept:C0028128,
umls-concept:C0030685,
umls-concept:C0225336,
umls-concept:C0243044,
umls-concept:C0391871,
umls-concept:C0392756,
umls-concept:C0600210,
umls-concept:C0680255,
umls-concept:C1283071,
umls-concept:C1825534,
umls-concept:C1963578
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pubmed:issue |
1
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pubmed:dateCreated |
2007-12-20
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pubmed:abstractText |
Heat-shock protein 90 (Hsp90) coordinates the regulation of diverse signaling proteins. We try to develop a new tool to explore the regulatory functions of Hsp90 in endothelial cells (ECs) instead of the existing chemical approaches.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1524-4636
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
105-11
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17975117-Adenoviridae,
pubmed-meshheading:17975117-Animals,
pubmed-meshheading:17975117-Cattle,
pubmed-meshheading:17975117-Cell Movement,
pubmed-meshheading:17975117-Cells, Cultured,
pubmed-meshheading:17975117-Endothelial Cells,
pubmed-meshheading:17975117-HSP90 Heat-Shock Proteins,
pubmed-meshheading:17975117-Lung,
pubmed-meshheading:17975117-Mice,
pubmed-meshheading:17975117-Mutagenesis, Site-Directed,
pubmed-meshheading:17975117-Nitric Oxide,
pubmed-meshheading:17975117-Nitric Oxide Synthase Type III,
pubmed-meshheading:17975117-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:17975117-Signal Transduction,
pubmed-meshheading:17975117-Vascular Endothelial Growth Factor A
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pubmed:year |
2008
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pubmed:articleTitle |
Dominant-negative Hsp90 reduces VEGF-stimulated nitric oxide release and migration in endothelial cells.
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pubmed:affiliation |
Department of Pharmacology and Vascular Biology and Therapeutics Program, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, CT 06536, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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