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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2007-11-2
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pubmed:abstractText |
Disasters are associated with increased risk of posttraumatic stress disorder (PTSD) and major depression, but no study, to the authors' knowledge, has determined whether genotype interacts with disaster exposure and social support to moderate risk of these phenotypes. The authors tested the hypothesis that a polymorphism in the serotonin transporter gene (locus, SLC6A4; variant, serotonin 5-HTTLPR) moderates risk of posthurricane PTSD and major depression given high hurricane exposure and low social support.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0002-953X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
164
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1693-9
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pubmed:dateRevised |
2011-5-5
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pubmed:meshHeading |
pubmed-meshheading:17974934-Adolescent,
pubmed-meshheading:17974934-Adult,
pubmed-meshheading:17974934-Depressive Disorder, Major,
pubmed-meshheading:17974934-Diagnostic and Statistical Manual of Mental Disorders,
pubmed-meshheading:17974934-Disasters,
pubmed-meshheading:17974934-Female,
pubmed-meshheading:17974934-Florida,
pubmed-meshheading:17974934-Genetic Variation,
pubmed-meshheading:17974934-Genotype,
pubmed-meshheading:17974934-Humans,
pubmed-meshheading:17974934-Life Change Events,
pubmed-meshheading:17974934-Logistic Models,
pubmed-meshheading:17974934-Male,
pubmed-meshheading:17974934-Middle Aged,
pubmed-meshheading:17974934-Polymorphism, Genetic,
pubmed-meshheading:17974934-Psychiatric Status Rating Scales,
pubmed-meshheading:17974934-Risk Factors,
pubmed-meshheading:17974934-Serotonin Plasma Membrane Transport Proteins,
pubmed-meshheading:17974934-Social Support,
pubmed-meshheading:17974934-Stress Disorders, Post-Traumatic
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pubmed:year |
2007
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pubmed:articleTitle |
The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults.
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pubmed:affiliation |
National Crime Victims Research and Treatment Center, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, P.O. Box 250852, Charleston, SC 29425, USA. kilpatdg@musc.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Extramural
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