Linked Life Data

17971512

Source:http://linkedlifedata.com/resource/pubmed/id/17971512

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:17971512rdf:typepubmed:Citationlld:pubmed
pubmed-article:17971512lifeskim:mentionsumls-concept:C0086418lld:lifeskim
pubmed-article:17971512lifeskim:mentionsumls-concept:C0242692lld:lifeskim
pubmed-article:17971512lifeskim:mentionsumls-concept:C0015259lld:lifeskim
pubmed-article:17971512lifeskim:mentionsumls-concept:C0220931lld:lifeskim
pubmed-article:17971512lifeskim:mentionsumls-concept:C0205341lld:lifeskim
pubmed-article:17971512lifeskim:mentionsumls-concept:C1515670lld:lifeskim
pubmed-article:17971512lifeskim:mentionsumls-concept:C1540067lld:lifeskim
pubmed-article:17971512lifeskim:mentionsumls-concept:C0683598lld:lifeskim
pubmed-article:17971512lifeskim:mentionsumls-concept:C0392747lld:lifeskim
pubmed-article:17971512lifeskim:mentionsumls-concept:C0205263lld:lifeskim
pubmed-article:17971512lifeskim:mentionsumls-concept:C0443172lld:lifeskim
pubmed-article:17971512pubmed:issue1lld:pubmed
pubmed-article:17971512pubmed:dateCreated2008-1-14lld:pubmed
pubmed-article:17971512pubmed:abstractTextThe gain in muscle mass as a result of resistance training is dependent on changes in both anabolic and catabolic reactions. A frequency of two to three exercise sessions per week is considered optimal for muscle gain in untrained individuals. Our hypothesis was that a second exercise session would enlarge the anabolic response and/or decrease the catabolic response. Eight male subjects performed resistance exercise on two occasions separated by 2 days. Muscle biopsies were taken from the vastus lateralis before and 15 min, 1 h, and 2 h after exercise. Exercise led to severalfold increases in phosphorylation of mTOR at Ser2448, p70 S6 kinase (p70S6k) at Ser424/Thr421 and Thr389, and ribosomal protein S6, which persisted for up to 2 h of recovery on both occasions. There was a tendency toward a larger effect of the second exercise on p70S6k and S6, but the difference did not reach statistical significance. The mRNA expression of MuRF-1, which increased after exercise, was 30% lower after the second exercise session than after the first one. MAFbx expression was not altered after exercise but downregulated 30% 48 h later, whereas myostatin expression was reduced by 45% after the first exercise and remained low until after the second exercise session. The results indicate that 1) changes in expression of genes involved in protein degradation are attenuated as a response to repetitive resistance training with minor additional increases in enzymes regulating protein synthesis and 2) the two ubiquitin ligases, MuRF-1 and MAFbx, are differently affected by the exercise as well as by repeated exercise.lld:pubmed
pubmed-article:17971512pubmed:languageenglld:pubmed
pubmed-article:17971512pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:citationSubsetIMlld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:17971512pubmed:statusMEDLINElld:pubmed
pubmed-article:17971512pubmed:monthJanlld:pubmed
pubmed-article:17971512pubmed:issn0193-1849lld:pubmed
pubmed-article:17971512pubmed:authorpubmed-author:EkblomBjörnBlld:pubmed
pubmed-article:17971512pubmed:authorpubmed-author:BlomstrandEva...lld:pubmed
pubmed-article:17971512pubmed:authorpubmed-author:GustafssonTho...lld:pubmed
pubmed-article:17971512pubmed:authorpubmed-author:Brink-Elfegou...lld:pubmed
pubmed-article:17971512pubmed:authorpubmed-author:MascherHenrik...lld:pubmed
pubmed-article:17971512pubmed:authorpubmed-author:TannerstedtJö...lld:pubmed
pubmed-article:17971512pubmed:issnTypePrintlld:pubmed
pubmed-article:17971512pubmed:volume294lld:pubmed
pubmed-article:17971512pubmed:ownerNLMlld:pubmed
pubmed-article:17971512pubmed:authorsCompleteYlld:pubmed
pubmed-article:17971512pubmed:paginationE43-51lld:pubmed
pubmed-article:17971512pubmed:dateRevised2010-11-18lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:meshHeadingpubmed-meshheading:17971512...lld:pubmed
pubmed-article:17971512pubmed:year2008lld:pubmed
pubmed-article:17971512pubmed:articleTitleRepeated resistance exercise training induces different changes in mRNA expression of MAFbx and MuRF-1 in human skeletal muscle.lld:pubmed
pubmed-article:17971512pubmed:affiliationAstrand Laboratory, Swedish School of Sport and Health Sciences, Karolinska University Hospital, Karolinska Institutet, Box 5626, Stockholm, S-114 86, Sweden.lld:pubmed
pubmed-article:17971512pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17971512pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
entrez-gene:84676entrezgene:pubmedpubmed-article:17971512lld:entrezgene
entrez-gene:114907entrezgene:pubmedpubmed-article:17971512lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:17971512lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:17971512lld:entrezgene
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17971512lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17971512lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17971512lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:17971512lld:pubmed