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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2007-11-26
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pubmed:abstractText |
Proteomic analysis has previously shown that activin A, a member of the transforming growth factor beta family, is produced by human articular cartilage. This study was undertaken to investigate whether activin A affects cartilage matrix catabolism and how its production is regulated.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/4(2'-aminoethyl)amino-1,8-dimethylim...,
http://linkedlifedata.com/resource/pubmed/chemical/Activins,
http://linkedlifedata.com/resource/pubmed/chemical/Aggrecans,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Endopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factor 2,
http://linkedlifedata.com/resource/pubmed/chemical/Imidazoles,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/PD 173074,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrimidines,
http://linkedlifedata.com/resource/pubmed/chemical/Quinoxalines,
http://linkedlifedata.com/resource/pubmed/chemical/SMAD2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Smad2 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/activin A,
http://linkedlifedata.com/resource/pubmed/chemical/aggrecanase
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3715-25
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pubmed:dateRevised |
2010-12-3
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pubmed:meshHeading |
pubmed-meshheading:17968943-Activins,
pubmed-meshheading:17968943-Aggrecans,
pubmed-meshheading:17968943-Animals,
pubmed-meshheading:17968943-Cartilage, Articular,
pubmed-meshheading:17968943-Cytokines,
pubmed-meshheading:17968943-Endopeptidases,
pubmed-meshheading:17968943-Fibroblast Growth Factor 2,
pubmed-meshheading:17968943-Fibroblasts,
pubmed-meshheading:17968943-Humans,
pubmed-meshheading:17968943-Imidazoles,
pubmed-meshheading:17968943-NF-kappa B,
pubmed-meshheading:17968943-Osteoarthritis, Knee,
pubmed-meshheading:17968943-Pyrimidines,
pubmed-meshheading:17968943-Quinoxalines,
pubmed-meshheading:17968943-Smad2 Protein,
pubmed-meshheading:17968943-Sus scrofa
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pubmed:year |
2007
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pubmed:articleTitle |
Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB.
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pubmed:affiliation |
Kennedy Institute of Rheumatology, Imperial College London, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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