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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2007-11-26
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pubmed:abstractText |
Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is characterized by necrotizing vessel wall inflammation, paralleled by the detachment of endothelial cells. The repair of such endothelial defects is crucial for the maintenance of regular structure and function of the injured vessels. Bone marrow-derived endothelial progenitor cells (EPCs) are thought to play a pivotal role in the regeneration of damaged endothelium. The aim of this study was to investigate whether EPCs are involved in vascular repair in AAV.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3847-53
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pubmed:meshHeading |
pubmed-meshheading:17968939-Antibodies, Antineutrophil Cytoplasmic,
pubmed-meshheading:17968939-Antigens, CD34,
pubmed-meshheading:17968939-Endothelial Cells,
pubmed-meshheading:17968939-Endothelium, Vascular,
pubmed-meshheading:17968939-Female,
pubmed-meshheading:17968939-Flow Cytometry,
pubmed-meshheading:17968939-Hematopoietic Stem Cells,
pubmed-meshheading:17968939-Humans,
pubmed-meshheading:17968939-Immunomagnetic Separation,
pubmed-meshheading:17968939-Immunosuppressive Agents,
pubmed-meshheading:17968939-Male,
pubmed-meshheading:17968939-Necrosis,
pubmed-meshheading:17968939-Treatment Outcome,
pubmed-meshheading:17968939-Vasculitis
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pubmed:year |
2007
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pubmed:articleTitle |
Vascular endothelial damage and repair in antineutrophil cytoplasmic antibody-associated vasculitis.
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pubmed:affiliation |
Hannover Medical School, Hannover, Germany. kirsten@de-groot.de
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pubmed:publicationType |
Journal Article,
Controlled Clinical Trial
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