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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1992-4-8
|
| pubmed:abstractText |
Tri-substituted benzamide derivatives are described as a new class of antiviral drugs. Three compounds (3, N-acetylaminobenzamide, 3, N-butyrylaminobenzamide, and 3-methoxybenzamide) protected mice inoculated with influenza type A virus. 3, N-acetylaminobenzamide was found to be most active. It is suggested that the antiviral effect may be due to the specific inhibitory action of these compounds on NAD(+)-dependent ADP-ribosylation.
|
| pubmed:language |
rus
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0507-4088
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
36
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
293-5
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1796583-Animals,
pubmed-meshheading:1796583-Antiviral Agents,
pubmed-meshheading:1796583-Benzamides,
pubmed-meshheading:1796583-Drug Evaluation, Preclinical,
pubmed-meshheading:1796583-Influenza A virus,
pubmed-meshheading:1796583-Lethal Dose 50,
pubmed-meshheading:1796583-Mice,
pubmed-meshheading:1796583-Orthomyxoviridae Infections,
pubmed-meshheading:1796583-Poly Adenosine Diphosphate Ribose
|
| pubmed:articleTitle |
[An experimental study of ADP-ribosylation inhibitors as anti-influenza agents].
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|