Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1992-4-9
pubmed:abstractText
Methodological improvements in nuclear magnetic resonance (NMR) imaging and spectroscopy have enabled the application of these techniques to the study of functional or dynamic biological processes. Because the techniques are non-invasive, repeated measurements can be made in the same animal at different time points, allowing disease progression and regression to be followed during drug therapy. In this review, Markus Rudin, Wolfgang Zierhut, André Sauter and Nigel Cook illustrate this concept by the use of NMR to evaluate cardiovascular function in the rat in various physiological and pathological situations. The possibility of using NMR to perform similar studies in both animals and humans should lead to the design of preclinical models with an improved clinical predictability.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0165-6147
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
416-21
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
New developments in cardiovascular magnetic resonance imaging and spectroscopy.
pubmed:affiliation
Central Functions Department, Sandoz Pharma, Basel, Switzerland.
pubmed:publicationType
Journal Article, Review