Linked Life Data

1796313

Source:http://linkedlifedata.com/resource/pubmed/id/1796313

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1992-4-7
pubmed:abstractText
Experiments were performed on 42 urethane-anesthetized rabbits of both sexes. The rabbits were either spontaneously breathing or gallamine paralyzed and artificially ventilated. Efferent phrenic nerve activity was recorded with bipolar silver electrodes. The experiment results were as follows: Unilateral mechanical lesion of focal block by microinjection of lidocaine (2%, 1 microliter) in the ventromedial region of nucleus facialis (VMNF) consistently caused apneustic-type breathing associated with no significant changes in the rate of rise of inspiratory activity. The expiratory time (Te) was only slightly affected or not changed at all. Some increase in Te was present only when a very strong apneustic effect was evoked. Respiratory effects of focal block by lidocaine in the region of VMNF were not accompanied by changes in blood pressure. No significant changes in respiratory rhythm were observed when lidocaine is microinjected in the nearby regions of VMNF. The results suggest that VMNF appears to be involved in an inspiratory off-switch mechanism.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0371-0874
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
499-503
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[Effects on respiratory rhythmicity by lesion or focal block in ventromedial region of nucleus facialis].
pubmed:affiliation
Department of Physiology, Shandong Medical University, Jinan.
pubmed:publicationType
Journal Article, English Abstract