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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2007-10-25
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pubmed:abstractText |
The downregulation of phospholamban (PLB) and FKBP12.6 as a result of beta- receptor activation is involved in the pathway(s) of congestive heart failure. We hypothesized that the endothelin (ET)-1 system may link to downregulated PLB and FKBP12.6.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic beta-Agonists,
http://linkedlifedata.com/resource/pubmed/chemical/CPU0213,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Isoproterenol,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrazoles,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Endothelin,
http://linkedlifedata.com/resource/pubmed/chemical/Tacrolimus Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/phospholamban,
http://linkedlifedata.com/resource/pubmed/chemical/tacrolimus binding protein 1B
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1671-4083
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1746-54
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pubmed:meshHeading |
pubmed-meshheading:17959025-Adrenergic beta-Agonists,
pubmed-meshheading:17959025-Animals,
pubmed-meshheading:17959025-Calcium-Binding Proteins,
pubmed-meshheading:17959025-Cells, Cultured,
pubmed-meshheading:17959025-Down-Regulation,
pubmed-meshheading:17959025-Heart,
pubmed-meshheading:17959025-Heart Failure,
pubmed-meshheading:17959025-Isoproterenol,
pubmed-meshheading:17959025-Male,
pubmed-meshheading:17959025-Myocytes, Cardiac,
pubmed-meshheading:17959025-Pyrazoles,
pubmed-meshheading:17959025-RNA, Messenger,
pubmed-meshheading:17959025-Rats,
pubmed-meshheading:17959025-Rats, Sprague-Dawley,
pubmed-meshheading:17959025-Receptors, Endothelin,
pubmed-meshheading:17959025-Tacrolimus Binding Proteins,
pubmed-meshheading:17959025-Ventricular Fibrillation
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pubmed:year |
2007
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pubmed:articleTitle |
Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12.6 by CPU0213-mediated antagonism of endothelin receptors.
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pubmed:affiliation |
Research Division of Pharmacology, China Pharmaceutical University, Nanjing 210009, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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